InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SPTA1

Summary

InnateDB Protein

IDBP-682383.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPTA1

Protein Name

spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053194

InnateDB Gene

IDBG-630820 (SPTA1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0002260	lymphocyte homeostasis
GO:0006779	porphyrin-containing compound biosynthetic process
GO:0007009	plasma membrane organization
GO:0008360	regulation of cell shape
GO:0030036	actin cytoskeleton organization
GO:0030097	hemopoiesis
GO:0032092	positive regulation of protein binding
GO:0042102	positive regulation of T cell proliferation

Cellular Component

GO:0014731	spectrin-associated cytoskeleton
GO:0016020	membrane
GO:0030863	cortical cytoskeleton
GO:0032437	cuticular plate

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR002017 Spectrin repeat
IPR002048 EF-hand domain
IPR011511 Variant SH3 domain
IPR013315 Spectrin alpha chain, SH3 domain
IPR014837 EF-hand, Ca insensitive
IPR018159 Spectrin/alpha-actinin

PFAM