InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PARP1

Summary

InnateDB Protein

IDBP-682614.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PARP1

Protein Name

poly

Synonyms

ADPRT; ARTD1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001113

InnateDB Gene

IDBG-631108 (PARP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 182 interaction(s) predicted by orthology.

Predicted by orthology
Total	182 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0019899	enzyme binding
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding
GO:0047485	protein N-terminus binding
GO:0051287	NAD binding

Biological Process

GO:0000723	telomere maintenance
GO:0006259	DNA metabolic process
GO:0006284	base-excision repair
GO:0006302	double-strand break repair
GO:0006471	protein ADP-ribosylation
GO:0032869	cellular response to insulin stimulus
GO:0040009	regulation of growth rate
GO:0070212	protein poly-ADP-ribosylation

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005654	nucleoplasm
GO:0005667	transcription factor complex
GO:0005730	nucleolus
GO:0016020	membrane
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001357 BRCT domain
IPR001510 Zinc finger, PARP-type
IPR004102 Poly(ADP-ribose) polymerase, regulatory domain
IPR008288 NAD+ ADP-ribosyltransferase
IPR008893 WGR domain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
IPR012982 PADR1

PFAM