InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GSTA4

Summary

InnateDB Protein

IDBP-684352.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GSTA4

Protein Name

Glutathione S-transferase A4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028640

InnateDB Gene

IDBG-632718 (GSTA4)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding
GO:0016740	transferase activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0006749	glutathione metabolic process
GO:0006805	xenobiotic metabolic process
GO:0008152	metabolic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR003080 Glutathione S-transferase, alpha class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM