InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KANSL2

Summary

InnateDB Protein

IDBP-684507.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KANSL2

Protein Name

Uncharacterized protein C12orf41 homolog

Synonyms

C12orf41; C5H12orf41; C5HANSL2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003489

InnateDB Gene

IDBG-632828 (KANSL2)

Protein Structure

UniProt Annotation

Function

As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0043995	histone acetyltransferase activity (H4-K5 specific)
GO:0043996	histone acetyltransferase activity (H4-K8 specific)
GO:0046972	histone acetyltransferase activity (H4-K16 specific)

Biological Process

GO:0016568	chromatin modification
GO:0043981	histone H4-K5 acetylation
GO:0043982	histone H4-K8 acetylation
GO:0043984	histone H4-K16 acetylation

Cellular Component

GO:0000123	histone acetyltransferase complex
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2NL14

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

540194

UniGene

Bt.15714

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC111221 BT021786

GenPept

AAI11222 AAX46633