Version 5.4
Homo sapiens Protein: ENDOD1
Summary
InnateDB Protein IDBP-68460.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENDOD1
Protein Name endonuclease domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000278505
InnateDB Gene IDBG-68458 (ENDOD1)
Protein Structure
UniProt Annotation
Function May act as a DNase and a RNase. {ECO:0000305}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001604 DNA/RNA non-specific endonuclease
IPR020821 Extracellular Endonuclease, subunit A
PFAM PF01223
PRINTS
PIRSF
SMART SM00892
SM00477
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94919
PhosphoSite PhosphoSite-O94919
TrEMBL
UniProt Splice Variant
Entrez Gene 23052
UniGene Hs.594553
RefSeq NP_055851
HUGO HGNC:29129
OMIM
CCDS CCDS41699
HPRD
IMGT
EMBL AB020637 AK291673 BC026191 BC071171
GenPept AAH26191 AAH71171 BAA74853 BAF84362

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca