Version 5.4
| Bos taurus Protein: ADCYAP1R1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-685088.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | ADCYAP1R1 | ||||||||||
| Protein Name | Pituitary adenylate cyclase-activating polypeptide type I receptor | ||||||||||
| Synonyms | PACAPR; | ||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000055102 | ||||||||||
| InnateDB Gene | IDBG-633373 (ADCYAP1R1) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR000832
GPCR, family 2, secretin-like IPR001879 GPCR, family 2, extracellular hormone receptor domain IPR002285 GPCR, family 2, pituitary adenylate cyclase activating polypeptide type 1 receptor IPR017981 GPCR, family 2-like |
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| PFAM |
PF00002
PF02793 |
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| PRINTS |
PR00249
PR01156 |
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| PIRSF | |||||||||||
| SMART |
SM00008
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q29627 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 319095 | ||||||||||
| UniGene | |||||||||||
| RefSeq | XP_005205545 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | D17290 | ||||||||||
| GenPept | BAA04122 BAA04123 | ||||||||||