InnateDB Protein
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IDBP-685146.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GGCT
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Protein Name
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Gamma-glutamylcyclotransferase
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Synonyms
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C7orf24;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000014010
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InnateDB Gene
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IDBG-633436 (GGCT)
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Protein Structure
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Function |
Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003839
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gamma-glutamylcyclotransferase activity
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GO:0016740
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transferase activity
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GO:0016746
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transferase activity, transferring acyl groups
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GO:0042803
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protein homodimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009288
AIG2-like
IPR013024
Butirosin biosynthesis, BtrG-like
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PFAM |
PF06094
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q32LE4
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
533374
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UniGene |
Bt.109947
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RefSeq |
NP_001032699
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC109622
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GenPept |
AAI09623
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