Version 5.4
Bos taurus Protein: KDM6A
Summary
InnateDB Protein IDBP-689890.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM6A
Protein Name
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004874
InnateDB Gene IDBG-637770 (KDM6A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0071558 histone demethylase activity (H3-K27 specific)
Biological Process
GO:0001701 in utero embryonic development
GO:0001843 neural tube closure
GO:0003007 heart morphogenesis
GO:0003016 respiratory system process
GO:0007507 heart development
GO:0010468 regulation of gene expression
GO:0021915 neural tube development
GO:0032525 somite rostral/caudal axis specification
GO:0035264 multicellular organism growth
GO:0048333 mesodermal cell differentiation
GO:0048568 embryonic organ development
GO:0048570 notochord morphogenesis
GO:0060070 canonical Wnt signaling pathway
GO:0071557 histone H3-K27 demethylation
GO:0072358 cardiovascular system development
Cellular Component
GO:0005634 nucleus
GO:0035097 histone methyltransferase complex
Protein Structure and Domains
PDB ID
InterPro IPR001440 Tetratricopeptide TPR1
IPR003347 JmjC domain
IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF00515
PF02373
PF08007
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00558
SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MV76
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:12637
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02073517 DAAA02073518 DAAA02073519 DAAA02073520 DAAA02073521 DAAA02073522 DAAA02073523 DAAA02073524 DAAA02073525
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca