Bos taurus Protein: PRPF4
Summary
InnateDB Protein IDBP-690370.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPF4
Protein Name U4/U6 small nuclear ribonucleoprotein Prp4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006004
InnateDB Gene IDBG-638298 (PRPF4)
Protein Structure
UniProt Annotation
Function Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus speckle {ECO:0000250}. Note=Colocalizes with spliceosomal snRNPs. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.
Predicted by orthology
Total 59 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0071001 U4/U6 snRNP
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR003648 Splicing factor motif
IPR014906 Pre-mRNA processing factor 4 (PRP4)-like
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08799
PRINTS PR00320
PIRSF
SMART SM00320
SM00500
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHE2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 508735
UniGene Bt.16360
RefSeq NP_001029502
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105270
GenPept AAI05271