InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PRSS12

Summary

InnateDB Protein

IDBP-692166.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRSS12

Protein Name

protease, serine, 12 (neurotrypsin, motopsin)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027594

InnateDB Gene

IDBG-639949 (PRSS12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005044	scavenger receptor activity
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006508	proteolysis
GO:0006887	exocytosis
GO:0006898	receptor-mediated endocytosis
GO:0031638	zymogen activation

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030424	axon
GO:0030425	dendrite
GO:0031410	cytoplasmic vesicle
GO:0043083	synaptic cleft
GO:0043195	terminal bouton
GO:0045202	synapse

Protein Structure and Domains

PDB ID

InterPro

IPR000001 Kringle
IPR001190 SRCR domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR013806 Kringle-like fold
IPR017448 SRCR-like domain

PFAM

PF00051
PF00530
PF00089

PRINTS

PR00258
PR00722

PIRSF

SMART

SM00130
SM00020
SM00202

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt