Version 5.4
Bos taurus Protein: TFAP2C
Summary
InnateDB Protein IDBP-693678.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFAP2C
Protein Name transcription factor AP-2 gamma
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002671
InnateDB Gene IDBG-641326 (TFAP2C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001829 trophectodermal cell differentiation
GO:0001942 hair follicle development
GO:0003334 keratinocyte development
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008584 male gonad development
GO:0019827 stem cell maintenance
GO:0021877 forebrain neuron fate commitment
GO:0021987 cerebral cortex development
GO:0030154 cell differentiation
GO:0030718 germ-line stem cell maintenance
GO:0035019 somatic stem cell maintenance
GO:0043588 skin development
GO:0045682 regulation of epidermis development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048733 sebaceous gland development
GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR008123 Transcription factor AP-2 gamma
IPR013854 Transcription factor AP-2, C-terminal
PFAM PF03299
PRINTS PR01751
PR01748
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0VC14
UniProt Splice Variant
Entrez Gene 511317
UniGene Bt.69920
RefSeq NP_001068977
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120401 DAAA02036360
GenPept AAI20402

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca