InnateDB Protein
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IDBP-69380.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SAP130
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Protein Name
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Sin3A-associated protein, 130kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000259235
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InnateDB Gene
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IDBG-69376 (SAP130)
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Protein Structure
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Function |
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. {ECO:0000269PubMed:12724404}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:15561718}.
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Disease Associations |
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Tissue Specificity |
Expressed in various cancer cell ines. {ECO:0000269PubMed:12724404}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
41
[view]
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Protein-Protein |
40
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003713
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transcription coactivator activity
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GO:0004402
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histone acetyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H0E3
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PhosphoSite |
PhosphoSite-Q9H0E3
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TrEMBL |
C9J683
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UniProt Splice Variant |
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Entrez Gene |
79595
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UniGene |
Hs.32995
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RefSeq |
NP_078821
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HUGO |
HGNC:29813
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OMIM |
609697
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CCDS |
CCDS2153
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HPRD |
18015
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IMGT |
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EMBL |
AC012306
AC118060
AK022823
AL136833
AY220791
BC017453
BC117255
BC143898
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GenPept |
AAH17453
AAI17256
AAI43899
AAO63591
AAX88975
AAY14878
BAB14261
CAB66767
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