InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NFS1

Summary

InnateDB Protein

IDBP-694689.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NFS1

Protein Name

cysteine desulfurase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009149

InnateDB Gene

IDBG-642247 (NFS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0016829	lyase activity
GO:0030170	pyridoxal phosphate binding
GO:0031071	cysteine desulfurase activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0006520	cellular amino acid metabolic process
GO:0006534	cysteine metabolic process
GO:0008152	metabolic process
GO:0018283	iron incorporation into metallo-sulfur cluster

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR000192 Aminotransferase class V domain
IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase
IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase
IPR010240 Cysteine desulfurase
IPR015424 Pyridoxal phosphate-dependent transferase
IPR016454 Cysteine desulfurase, NifS

PFAM

PF00266
PF01041
PF01212

PRINTS

PIRSF

PIRSF000390
PIRSF005572

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite