InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PCBP1

Summary

InnateDB Protein

IDBP-700983.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCBP1

Protein Name

Poly(rC)-binding protein 1

Synonyms

hnRNP-E1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000049383

InnateDB Gene

IDBG-648221 (PCBP1)

Protein Structure

UniProt Annotation

Function

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.

Predicted by orthology
Total	85 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003697	single-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004044 K Homology domain, type 2
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1

PFAM

PF07650
PF00013
PF13014

PRINTS

PIRSF

SMART

SM00322

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9A3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

509917

UniGene

Bt.4620

RefSeq

NP_001015565

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BT021017

GenPept

AAX09034