Version 5.4
Homo sapiens Protein: COX6B2
Summary
InnateDB Protein IDBP-70563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX6B2
Protein Name cytochrome c oxidase subunit VIb polypeptide 2 (testis)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000320672
InnateDB Gene IDBG-70561 (COX6B2)
Protein Structure
UniProt Annotation
Function Connects the two COX monomers into the physiological dimeric form. {ECO:0000250}.
Subcellular Localization Mitochondrion intermembrane space {ECO:0000250}.
Disease Associations
Tissue Specificity Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines. {ECO:0000269PubMed:12874793, ECO:0000269PubMed:15905330}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
Biological Process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0030061 mitochondrial crista
Protein Structure and Domains
PDB ID
InterPro IPR003213 Cytochrome c oxidase, subunit VIb
PFAM PF02297
PRINTS
PIRSF PIRSF000278
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6YFQ2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 125965
UniGene Hs.736127
RefSeq NP_653214
HUGO HGNC:24380
OMIM
CCDS CCDS42630
HPRD 13088
IMGT
EMBL AK057427 AY152398 BC026123 BC100899 BC100900 BC100901 BC100902
GenPept AAH26123 AAI00900 AAI00901 AAI00902 AAI00903 AAN46751 BAB71481

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca