Mus musculus Protein: Dnajb11
Summary
InnateDB Protein IDBP-706396.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajb11
Protein Name
Synonyms 1810031F23Rik; ABBP-2; AL024055; Dj9; ERdj3; ERj3p;
Species Mus musculus
Ensembl Protein ENSMUSP00000137542
InnateDB Gene IDBG-148626 (Dnajb11)
Protein Structure
UniProt Annotation
Function Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000269PubMed:15525676}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0016556 mRNA modification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:1915088
InterPro IPR001623 DnaJ domain
IPR002939 Chaperone DnaJ, C-terminal
IPR008971 HSP40/DnaJ peptide-binding
PFAM PF00226
PF01556
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99KV1
PhosphoSite PhosphoSite-Q99KV1
TrEMBL
UniProt Splice Variant
Entrez Gene 67838
UniGene Mm.477367
RefSeq NP_001177734
MGI ID
MGI Symbol Dnajb11
OMIM
CCDS CCDS28070
HPRD
IMGT
EMBL AK050500 AK075785 AK075953 AK148511 AK166730 AY054981 BC003999 BC018282 BC040747 CT027991
GenPept AAH03999 AAH18282 AAH40747 AAL17676 BAC34293 BAC35956 BAC36079 BAE28593 BAE38977 CAO78022