InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ITPKA

Summary

InnateDB Protein

IDBP-7099.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITPKA

Protein Name

inositol-trisphosphate 3-kinase A

Synonyms

IP3-3KA; IP3KA;

Species

Homo sapiens

Ensembl Protein

ENSP00000260386

InnateDB Gene

IDBG-7097 (ITPKA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004683	calmodulin-dependent protein kinase activity
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
GO:0048365	Rac GTPase binding

Biological Process

GO:0006020	inositol metabolic process
GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0030036	actin cytoskeleton organization
GO:0043647	inositol phosphate metabolic process
GO:0044281	small molecule metabolic process
GO:0048167	regulation of synaptic plasticity
GO:0061003	positive regulation of dendritic spine morphogenesis
GO:0097062	dendritic spine maintenance