InnateDB Protein
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IDBP-71851.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZNF22
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Protein Name
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zinc finger protein 22 (KOX 15)
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Synonyms
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HKR-T1; KOX15; Zfp422; ZNF422;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000298299
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InnateDB Gene
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IDBG-71849 (ZNF22)
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Protein Structure
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Function |
Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
In the embryo, expressed in developing craniofacial structures including dental epithelium of maxillary molar tooth organs, tongue epithelium and muscle, and craniofacial bone osteoblasts. In the adult, expressed in mesoderm-derived tissues such as skeletal muscle, heart, kidney and liver. Intermediate expression in spleen, thymus and brain. Low levels in endoderm-derived tissues such as intestine and colon. {ECO:0000269PubMed:14630903}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
18
[view]
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Protein-Protein |
17
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
P17026
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PhosphoSite |
PhosphoSite-P17026
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TrEMBL |
A0A024R7T4
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UniProt Splice Variant |
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Entrez Gene |
7570
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UniGene |
Hs.667604
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RefSeq |
NP_008894
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HUGO |
HGNC:13012
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OMIM |
194529
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CCDS |
CCDS7211
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HPRD |
01917
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IMGT |
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EMBL |
AK291508
AL353801
AY137767
BC010642
BC041139
BC053687
BT009806
CH471160
M77172
S50223
X52346
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GenPept |
AAA36815
AAB24264
AAH10642
AAH41139
AAH53687
AAN15804
AAP88808
BAF84197
CAA36572
CAI13068
EAW86632
EAW86633
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