InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ddx27

Summary

InnateDB Protein

IDBP-718839.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ddx27

Protein Name

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135265

InnateDB Gene

IDBG-212986 (Ddx27)

Protein Structure

UniProt Annotation

Function

Probable ATP-dependent RNA helicase.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:2385884

InterPro

IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00270

PRINTS

PIRSF

SMART

SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q921N6