Version 5.4
Homo sapiens Protein: MBD1
Summary
InnateDB Protein IDBP-725783.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MBD1
Protein Name
Synonyms CXXC3; PCM1; RFT;
Species Homo sapiens
Ensembl Protein ENSP00000468785
InnateDB Gene IDBG-3349 (MBD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 50 [view]
Protein-Protein 44 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008327 methyl-CpG binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0000785 chromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro IPR001739 Methyl-CpG DNA binding
IPR002857 Zinc finger, CXXC-type
IPR016177 DNA-binding domain
PFAM PF01429
PF02008
PRINTS
PIRSF
SMART SM00391
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UIS9
PhosphoSite PhosphoSite-Q9UIS9
TrEMBL
UniProt Splice Variant
Entrez Gene 4152
UniGene Hs.732970
RefSeq NP_001191065
HUGO HGNC:6916
OMIM 156535
CCDS CCDS59320
HPRD 01133
IMGT
EMBL AC090246 AF072241 AF078830 AF078831 AF078832 AF078833 AF120980 AF120981 AJ564845 AK302004 BC033242 EF488685 Y10746
GenPept AAC68870 AAD50371 AAD51442 AAD51443 AAD51444 AAD51445 AAH33242 ABP02056 BAG63407 CAA71735 CAD92308

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca