Version 5.4
Homo sapiens Protein: MEP1B
Summary
InnateDB Protein IDBP-727594.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEP1B
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000463280
InnateDB Gene IDBG-2209 (MEP1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR000998 MAM domain
IPR001506 Peptidase M12A, astacin
IPR002083 MATH
IPR006026 Peptidase, metallopeptidase
IPR008294 Meprin alpha/beta subunit
IPR008974 TRAF-like
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00008
PF00629
PF01400
PF00917
PRINTS PR00020
PR00480
PIRSF PIRSF001196
SMART SM00181
SM00137
SM00061
SM00235
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3QKX5
UniProt Splice Variant
Entrez Gene 4225
UniGene Hs.194777
RefSeq XP_005258332
HUGO HGNC:7020
OMIM 600389
CCDS
HPRD 02667
IMGT
EMBL AC011825 AC015563 CH471088
GenPept EAX01284

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca