Version 5.4
Homo sapiens Protein: MTMR8
Summary
InnateDB Protein IDBP-73188.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTMR8
Protein Name myotubularin related protein 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000363985
InnateDB Gene IDBG-73186 (MTMR8)
Protein Structure
UniProt Annotation
Function Phosphatase that acts on lipids with a phosphoinositol headgroup. {ECO:0000305}.
Subcellular Localization Nucleus envelope {ECO:0000269PubMed:16787938}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005635 nuclear envelope
Protein Structure and Domains
PDB ID
InterPro IPR003595 Protein-tyrosine phosphatase, catalytic
IPR010569 Myotubularin-like phosphatase domain
IPR029021 Protein-tyrosine phosphatase-like
PFAM PF06602
PRINTS
PIRSF
SMART SM00404
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96EF0
PhosphoSite PhosphoSite-Q96EF0
TrEMBL
UniProt Splice Variant
Entrez Gene 55613
UniGene Hs.442892
RefSeq NP_060147
HUGO HGNC:16825
OMIM
CCDS CCDS14379
HPRD 06664
IMGT
EMBL AK000133 AL034408 AL356317 BC012399 CH471132
GenPept AAH12399 BAA90964 CAI39933 CAI39934 CAI43024 CAI43025 EAX05411

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca