InnateDB Protein
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IDBP-73861.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RPN2
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Protein Name
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ribophorin II
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Synonyms
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RIBIIR; RPN-II; RPNII; SWP1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000362724
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InnateDB Gene
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IDBG-73849 (RPN2)
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Protein Structure
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Function |
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in all tissues tested.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
44
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004579
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dolichyl-diphosphooligosaccharide-protein glycotransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008814
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1
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PFAM |
PF05817
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P04844
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PhosphoSite |
PhosphoSite-P04844
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
6185
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UniGene |
Hs.370895
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RefSeq |
NP_001129243
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HUGO |
HGNC:10382
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OMIM |
180490
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CCDS |
CCDS46599
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HPRD |
01609
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IMGT |
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EMBL |
AJ237733
AJ237734
AJ237735
AJ237736
AJ237737
AJ237738
AJ237739
AJ237740
AJ237741
AJ237742
AJ237743
AJ237744
AJ237745
AJ237746
AJ237747
AJ237748
AJ237749
AK096243
AL031659
BC002380
BC003560
BC013028
BC020222
CH471077
CR456899
Y00282
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GenPept |
AAH02380
AAH03560
AAH13028
AAH20222
BAG53237
CAA68393
CAB41763
CAB54801
CAG33180
CAI42668
EAW76073
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