InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRKG1

Summary

InnateDB Protein

IDBP-74555.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRKG1

Protein Name

protein kinase, cGMP-dependent, type I

Synonyms

1; AAT8; cGK; cGK 1; cGK1; cGKI; cGKI-alpha; cGKI-BETA; PKG; PRKG1B; PRKGR1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000363087

InnateDB Gene

IDBG-74547 (PRKG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	29 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004692	cGMP-dependent protein kinase activity
GO:0005524	ATP binding

Biological Process

GO:0006468

protein phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000595 Cyclic nucleotide-binding domain
IPR002373 cAMP/cGMP-dependent protein kinase
IPR002374 cGMP-dependent kinase
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF00027

PRINTS

PR00103
PR00104

PIRSF

SMART

SM00100

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt