Version 5.4
Homo sapiens Protein: TEX11
Summary
InnateDB Protein IDBP-74616.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TEX11
Protein Name testis expressed 11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000363440
InnateDB Gene IDBG-74610 (TEX11)
Protein Structure
UniProt Annotation
Function Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers (By similarity). {ECO:0000250}.
Subcellular Localization Chromosome {ECO:0000250}. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes. {ECO:0000250}.
Disease Associations
Tissue Specificity Testis-specific. Not expressed in adult ovaries. {ECO:0000269PubMed:18369460}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006311 meiotic gene conversion
GO:0007131 reciprocal meiotic recombination
Cellular Component
GO:0000795 synaptonemal complex
Protein Structure and Domains
PDB ID
InterPro IPR013940 Meiosis specific protein SPO22
IPR019734 Tetratricopeptide repeat
PFAM PF08631
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IYF3
PhosphoSite PhosphoSite-Q8IYF3
TrEMBL
UniProt Splice Variant
Entrez Gene 56159
UniGene Hs.121776
RefSeq
HUGO HGNC:11733
OMIM 300311
CCDS
HPRD 02256
IMGT
EMBL AF285594 AK057391 AK057523 AK292471 AL139109 AL627071 AL627390 BC036016 CH471132
GenPept AAH36016 AAK31973 BAB71465 BAB71520 BAF85160 CAI39957 CAI39958 CAI40155 CAI41495 CAI41496 EAX05331

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca