Homo sapiens Protein: OGFOD1
Summary
InnateDB Protein IDBP-747092.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OGFOD1
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000457746
InnateDB Gene IDBG-31955 (OGFOD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 34 [view]
Protein-Protein 33 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 L-ascorbic acid binding
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031544 peptidyl-proline 3-dioxygenase activity
Biological Process
GO:0006449 regulation of translational termination
GO:0008283 cell proliferation
GO:0018126 protein hydroxylation
GO:0019511 peptidyl-proline hydroxylation
GO:0034063 stress granule assembly
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
Protein Structure and Domains
PDB ID
InterPro IPR006620 Prolyl 4-hydroxylase, alpha subunit
IPR019601 Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain
PFAM PF10637
PRINTS
PIRSF
SMART SM00702
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N543
PhosphoSite PhosphoSite-Q8N543
TrEMBL H3BP48
UniProt Splice Variant
Entrez Gene 55239
UniGene Hs.682310
RefSeq
HUGO HGNC:25585
OMIM 615857
CCDS
HPRD 08553
IMGT
EMBL AB046832 AC092140 AK001688 AK022130 AK022752 AK024314 BC032919
GenPept AAH32919 BAA91838 BAB13438 BAB13967 BAB14226 BAB14880