Version 5.4
Homo sapiens Protein: EARS2
Summary
InnateDB Protein IDBP-747409.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EARS2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000456218
InnateDB Gene IDBG-20527 (EARS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
Biological Process
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000924 Glutamyl/glutaminyl-tRNA synthetase
IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial
IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding
IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
PFAM PF00749
PRINTS PR00987
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BRF5
UniProt Splice Variant
Entrez Gene 124454
UniGene Hs.643812
RefSeq XP_006721083
HUGO HGNC:29419
OMIM 612799
CCDS
HPRD
IMGT
EMBL AC002400 CH471145
GenPept EAW55823

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca