Version 5.4
Homo sapiens Protein: ZMYM3
Summary
InnateDB Protein IDBP-75387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZMYM3
Protein Name zinc finger, MYM-type 3
Synonyms DXS6673E; MYM; XFIM; ZNF198L2; ZNF261;
Species Homo sapiens
Ensembl Protein ENSP00000363110
InnateDB Gene IDBG-75385 (ZMYM3)
Protein Structure
UniProt Annotation
Function Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269PubMed:21834987}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations Note=A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).
Tissue Specificity Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007275 multicellular organismal development
GO:0022604 regulation of cell morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR010507 Zinc finger, MYM-type
IPR011017 TRASH domain
IPR021893 Protein of unknown function DUF3504
PFAM PF06467
PF12012
PRINTS
PIRSF
SMART SM00746
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14202
PhosphoSite PhosphoSite-Q14202
TrEMBL
UniProt Splice Variant
Entrez Gene 9203
UniGene Hs.522684
RefSeq NP_001164633
HUGO HGNC:13054
OMIM 300061
CCDS CCDS55444
HPRD 02088
IMGT
EMBL AB002383 AL590762 BC013009 BC069057 BT007095 CH471132 X95808
GenPept AAH13009 AAH69057 AAP35759 BAA20839 CAA65075 EAX05302 EAX05303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca