InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CYLD

Summary

InnateDB Protein

IDBP-754305.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYLD

Protein Name

Synonyms

BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1; SBS; TEM; USPL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000462134

InnateDB Gene

IDBG-30697 (CYLD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 76 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	76 [view]
Protein-Protein	70 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0005813	centrosome

Protein Structure and Domains

PDB ID

InterPro

IPR000938 CAP Gly-rich domain
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF01302
PF00443

PRINTS

PIRSF

SMART

SM01052

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite