InnateDB Protein
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IDBP-754404.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TSC2
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Protein Name
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Synonyms
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LAM; PPP1R160; TSC4;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000455817
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InnateDB Gene
|
IDBG-9819 (TSC2)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 115 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated |
Total |
115
[view]
|
Protein-Protein |
112
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
|
DNA-DNA |
1
[view]
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
14 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0005096
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GTPase activator activity
|
|
Biological Process |
GO:0051056
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regulation of small GTPase mediated signal transduction
|
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Cellular Component |
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PDB ID |
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InterPro |
IPR000331
Rap GTPase activating protein domain
|
PFAM |
PF02145
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
7249
|
UniGene |
Hs.90303
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RefSeq |
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HUGO |
HGNC:12363
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OMIM |
191092
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CCDS |
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HPRD |
01850
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IMGT |
|
EMBL |
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GenPept |
|
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