Homo sapiens Protein: ELAVL1
Summary
InnateDB Protein IDBP-760607.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELAVL1
Protein Name
Synonyms ELAV1; Hua; HUR; MelG;
Species Homo sapiens
Ensembl Protein ENSP00000472197
InnateDB Gene IDBG-24117 (ELAVL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 622 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 622 [view]
Protein-Protein 105 [view]
Protein-DNA 0
Protein-RNA 515 [view]
DNA-DNA 1 [view]
RNA-RNA 1 [view]
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0017091 AU-rich element binding
GO:0019901 protein kinase binding
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
GO:0007275 multicellular organismal development
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0045087 innate immune response (InnateDB)
GO:0045727 positive regulation of translation
GO:0048255 mRNA stabilization
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:2000036 regulation of stem cell maintenance
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR002343 Paraneoplastic encephalomyelitis antigen
IPR006548 Splicing factor ELAV/HuD
PFAM PF00076
PRINTS PR00961
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15717
PhosphoSite PhosphoSite-Q15717
TrEMBL B4DVB8
UniProt Splice Variant
Entrez Gene 1994
UniGene Hs.713744
RefSeq
HUGO HGNC:3312
OMIM 603466
CCDS CCDS12193
HPRD 16025
IMGT
EMBL AC008975 AC010336 AK301013 BC003376 BT009793 CH471139 U38175
GenPept AAB41913 AAH03376 AAP88795 BAG62630 EAW68949