InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GNL1

Summary

InnateDB Protein

IDBP-76086.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNL1

Protein Name

guanine nucleotide binding protein-like 1

Synonyms

HSR1;

Species

Homo sapiens

Ensembl Protein

ENSP00000365806

InnateDB Gene

IDBG-76084 (GNL1)

Protein Structure

UniProt Annotation

Function

Possible regulatory or functional link with the histocompatibility cluster.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	10 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005198	structural molecule activity
GO:0005525	GTP binding

Biological Process

GO:0002456	T cell mediated immunity
GO:0006184	GTP catabolic process
GO:0006974	cellular response to DNA damage stimulus
GO:0007165	signal transduction
GO:0042254	ribosome biogenesis

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR006073 GTP binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01926

PRINTS

PR00326

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P36915

PhosphoSite

PhosphoSite-P36915

TrEMBL

Q96QB8

UniProt Splice Variant

Entrez Gene

2794

UniGene

Hs.83147

RefSeq

NP_005266

HUGO

HGNC:4413

OMIM

143024

CCDS

CCDS4680

HPRD

00879

IMGT

EMBL

AB202092 AK293596 AK298042 AL662800 AL662825 BA000025 BC013959 BC018366 BC063657 BT006648 BX000357 BX248518 BX927220 CH471081 CR388372 CR936927 L25665

GenPept

AAA66492 AAH13959 AAH18366 AAH63657 AAP35294 BAB63327 BAE78611 BAG57062 BAG60340 CAI17831 CAI18152 CAI18558 CAM26012 CAQ07868 CAQ08501 CAQ09053 EAX03294 EAX03295