InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GFAP

Summary

InnateDB Protein

IDBP-761046.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GFAP

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000468500

InnateDB Gene

IDBG-54485 (GFAP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	36 [view]
Protein-Protein	36 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005198	structural molecule activity
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0019900	kinase binding

Biological Process

GO:0009611	response to wounding
GO:0010625	positive regulation of Schwann cell proliferation
GO:0010977	negative regulation of neuron projection development
GO:0014002	astrocyte development
GO:0030198	extracellular matrix organization
GO:0031102	neuron projection regeneration
GO:0045103	intermediate filament-based process
GO:0045109	intermediate filament organization
GO:0051580	regulation of neurotransmitter uptake
GO:0060020	Bergmann glial cell differentiation
GO:0060252	positive regulation of glial cell proliferation
GO:0060291	long-term synaptic potentiation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005882	intermediate filament
GO:0016020	membrane
GO:0042995	cell projection
GO:0044297	cell body
GO:0097449	astrocyte projection