InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: P4HB

Summary

InnateDB Protein

IDBP-762239.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P4HB

Protein Name

Synonyms

DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB;

Species

Homo sapiens

Ensembl Protein

ENSP00000461791

InnateDB Gene

IDBG-72655 (P4HB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 89 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	89 [view]
Protein-Protein	89 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016209	antioxidant activity
GO:0016491	oxidoreductase activity
GO:0016853	isomerase activity

Biological Process

GO:0008152	metabolic process
GO:0045454	cell redox homeostasis
GO:0055114	oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
IPR005788 Disulphide isomerase
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain

PFAM

PF00578
PF13098
PF13192
PF13462
PF13905
PF00085

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-