Homo sapiens Protein: PIRT | |||
---|---|---|---|
Summary | |||
InnateDB Protein | IDBP-763515.3 | ||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
Gene Symbol | PIRT | ||
Protein Name | |||
Synonyms | |||
Species | Homo sapiens | ||
Ensembl Protein | ENSP00000462046 | ||
InnateDB Gene | IDBG-301062 (PIRT) | ||
Protein Structure | |||
UniProt Annotation | |||
Function | Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity). {ECO:0000250}. | ||
Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||
Disease Associations | |||
Tissue Specificity | |||
Comments | |||
Interactions | |||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||
Gene Ontology | |||
Molecular Function |
|
||
Biological Process |
|
||
Cellular Component |
|
||
Protein Structure and Domains | |||
PDB ID | |||
InterPro | |||
PFAM | |||
PRINTS | |||
PIRSF | |||
SMART | |||
TIGRFAMs | |||
Post-translational Modifications | |||
Modification | |||
Cross-References | |||
SwissProt | P0C851 | ||
PhosphoSite | PhosphoSite- | ||
TrEMBL | |||
UniProt Splice Variant | |||
Entrez Gene | 644139 | ||
UniGene | Hs.553909 | ||
RefSeq | NP_001094857 | ||
HUGO | HGNC:37239 | ||
OMIM | 612068 | ||
CCDS | CCDS45614 | ||
HPRD | |||
IMGT | |||
EMBL | AC015908 AK299808 CH471108 DC332889 | ||
GenPept | BAH13134 EAW89989 | ||