Version 5.4
Homo sapiens Protein: ERCC1
Summary
InnateDB Protein IDBP-764412.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERCC1
Protein Name
Synonyms COFS4; RAD10; UV20;
Species Homo sapiens
Ensembl Protein ENSP00000468548
InnateDB Gene IDBG-57509 (ERCC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 23 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003684 damaged DNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR004579 DNA repair protein rad10
IPR010994 RuvA domain 2-like
IPR011335 Restriction endonuclease type II-like
PFAM PF03834
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7ES46
UniProt Splice Variant
Entrez Gene 2067
UniGene Hs.672821
RefSeq
HUGO HGNC:3433
OMIM 126380
CCDS
HPRD 00533
IMGT
EMBL AC092309 AC138128 AC138534 AC139353
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca