InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RUVBL2

Summary

InnateDB Protein

IDBP-765062.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUVBL2

Protein Name

Synonyms

ECP51; INO80J; REPTIN; RVB2; TIH2; TIP48; TIP49B;

Species

Homo sapiens

Ensembl Protein

ENSP00000469189

InnateDB Gene

IDBG-61221 (RUVBL2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 239 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	240 [view]
Protein-Protein	237 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003678	DNA helicase activity
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006260	DNA replication
GO:0032508	DNA duplex unwinding

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR003959 ATPase, AAA-type, core
IPR007694 DNA helicase, DnaB-like, C-terminal
IPR010339 TIP49, C-terminal
IPR011704 ATPase, dynein-related, AAA domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF03796
PF06068
PF07728

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-