Version 5.4
Homo sapiens Protein: GPX4
Summary
InnateDB Protein IDBP-765805.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPX4
Protein Name
Synonyms GPx-4; GSHPx-4; MCSP; PHGPx; snGPx; snPHGPx;
Species Homo sapiens
Ensembl Protein ENSP00000466872
InnateDB Gene IDBG-13826 (GPX4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004602 glutathione peroxidase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000889 Glutathione peroxidase
IPR012336 Thioredoxin-like fold
PFAM PF00255
PF13098
PF13192
PF13462
PF13905
PRINTS PR01011
PIRSF PIRSF000303
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 2879
UniGene Hs.601590
RefSeq
HUGO HGNC:4556
OMIM 138322
CCDS
HPRD 11819
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca