InnateDB Protein
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IDBP-76765.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PKIG
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Protein Name
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protein kinase (cAMP-dependent, catalytic) inhibitor gamma
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Synonyms
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PKI-gamma;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000338067
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InnateDB Gene
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IDBG-76749 (PKIG)
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Protein Structure
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Function |
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004862
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cAMP-dependent protein kinase inhibitor activity
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Biological Process |
GO:0006469
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negative regulation of protein kinase activity
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GO:0071901
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negative regulation of protein serine/threonine kinase activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR004171
cAMP-dependent protein kinase inhibitor
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PFAM |
PF02827
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PRINTS |
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PIRSF |
PIRSF001667
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y2B9
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PhosphoSite |
PhosphoSite-Q9Y2B9
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TrEMBL |
Q549H9
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UniProt Splice Variant |
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Entrez Gene |
11142
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UniGene |
Hs.472831
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RefSeq |
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HUGO |
HGNC:9019
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OMIM |
604932
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CCDS |
CCDS13334
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HPRD |
05379
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IMGT |
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EMBL |
AB019517
AF115966
AF182032
AK312048
BC104256
BC104257
CH471077
Z97053
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GenPept |
AAD55445
AAI04257
AAI04258
AAP97238
BAA77336
BAG34984
CAC18874
EAW75908
EAW75910
EAW75911
EAW75912
EAW75913
EAW75914
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