InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RBPJL

Summary

InnateDB Protein

IDBP-77462.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBPJL

Protein Name

recombination signal binding protein for immunoglobulin kappa J region-like

Synonyms

RBPSUHL; SUHL;

Species

Homo sapiens

Ensembl Protein

ENSP00000361828

InnateDB Gene

IDBG-77456 (RBPJL)

Protein Structure

UniProt Annotation

Function

Putative transcription factor, which cooperates with EBNA2 to activate transcription. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007165	signal transduction

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR008967 p53-like transcription factor, DNA-binding
IPR014756 Immunoglobulin E-set
IPR015350 Beta-trefoil DNA-binding domain
IPR015351 LAG1, DNA binding

PFAM

PF09270
PF09271

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UBG7

PhosphoSite