Version 5.4
Homo sapiens Protein: SH3BGRL
Summary
InnateDB Protein IDBP-78326.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3BGRL
Protein Name SH3 domain binding glutamic acid-rich protein like
Synonyms HEL-S-115; SH3BGR;
Species Homo sapiens
Ensembl Protein ENSP00000362308
InnateDB Gene IDBG-78324 (SH3BGRL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0017124 SH3 domain binding
Biological Process
GO:0009967 positive regulation of signal transduction
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR006993 SH3-binding, glutamic acid-rich protein
IPR012336 Thioredoxin-like fold
PFAM PF04908
PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF PIRSF008142
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75368
PhosphoSite PhosphoSite-O75368
TrEMBL V9HW48
UniProt Splice Variant
Entrez Gene 6451
UniGene Hs.108029
RefSeq NP_003013
HUGO HGNC:10823
OMIM 300190
CCDS CCDS14449
HPRD 02178
IMGT
EMBL AF042081 AK315897 AL136718 AL357115 BC016709 BC103762 CH471104 CR533478 FJ224348
GenPept AAC27445 AAH16709 AAI03763 ACI46040 BAF98788 CAB66652 CAG38509 CAI39436 EAW98579 EAW98580 EAW98581

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca