InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tcf12

Summary

InnateDB Protein

IDBP-789112.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tcf12

Protein Name

transcription factor 12

Synonyms

A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt; HTF-4; HTF4; ME1; REB;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000139365

InnateDB Gene

IDBG-183195 (Tcf12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	20 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0043425	bHLH transcription factor binding
GO:0044212	transcription regulatory region DNA binding
GO:0046332	SMAD binding
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0010628	positive regulation of gene expression
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:101877

InterPro

IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain

PFAM

PF00010

PRINTS

PIRSF

SMART

SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61286

PhosphoSite

PhosphoSite-Q61286

TrEMBL

UniProt Splice Variant

Entrez Gene

21406

UniGene

RefSeq

NP_035674

MGI ID

MGI Symbol

Tcf12

OMIM

CCDS

CCDS23329

HPRD

IMGT

EMBL

AC093483 AC157575 AC159001 M97635 M97636 X64840

GenPept

CAA46052