Version 5.4
Mus musculus Protein: Hck
Summary
InnateDB Protein IDBP-790110.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hck
Protein Name hemopoietic cell kinase
Synonyms AI849071; Bmk;
Species Mus musculus
Ensembl Protein ENSMUSP00000139988
InnateDB Gene IDBG-209984 (Hck)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006909 phagocytosis
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
Protein Structure and Domains
PDB ID MGI:96052
InterPro IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR011511 Variant SH3 domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF00017
PF14633
PF07714
PF00018
PF14604
PF07653
PRINTS PR00401
PR00109
PR00452
PIRSF
SMART SM00252
SM00326
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6UND7
UniProt Splice Variant
Entrez Gene 15162
UniGene
RefSeq
MGI ID
MGI Symbol Hck
OMIM
CCDS CCDS38284
HPRD
IMGT
EMBL AL807380 AL928862 BX682228
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca