Version 5.4
Homo sapiens Protein: HNRNPH2
Summary
InnateDB Protein IDBP-79811.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNRNPH2
Protein Name heterogeneous nuclear ribonucleoprotein H2 (H')
Synonyms FTP3; hnRNPH\'; HNRPH\'; HNRPH2;
Species Homo sapiens
Ensembl Protein ENSP00000361927
InnateDB Gene IDBG-79809 (HNRNPH2)
Protein Structure
UniProt Annotation
Function This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).
Subcellular Localization Nucleus, nucleoplasm.
Disease Associations
Tissue Specificity Expressed ubiquitously.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 85 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 85 [view]
Protein-Protein 85 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0008380 RNA splicing
GO:0010467 gene expression
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR012996 Zinc finger, CHHC-type
PFAM PF00076
PF08080
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55795
PhosphoSite PhosphoSite-P55795
TrEMBL
UniProt Splice Variant
Entrez Gene 3188
UniGene Hs.596084
RefSeq NP_062543
HUGO HGNC:5042
OMIM 300610
CCDS CCDS14485
HPRD 03022
IMGT
EMBL AL035422 BC130343 BC130345 CH471115 U01923 U78027
GenPept AAB64202 AAI30344 AAI30346 CAB55879 EAX02864

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca