Version 5.4
Homo sapiens Protein: PLCG1
Summary
InnateDB Protein IDBP-806633.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLCG1
Protein Name phospholipase C, gamma 1
Synonyms NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1;
Species Homo sapiens
Ensembl Protein ENSP00000476757
InnateDB Gene IDBG-75238 (PLCG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 237 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 237 [view]
Protein-Protein 236 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
PFAM PF00168
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL V9GY71
UniProt Splice Variant
Entrez Gene 5335
UniGene
RefSeq
HUGO HGNC:9065
OMIM 172420
CCDS
HPRD
IMGT
EMBL AL022394
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca