InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABCG4

Summary

InnateDB Protein

IDBP-809953.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCG4

Protein Name

ATP-binding cassette, sub-family G (WHITE), member 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000481728

InnateDB Gene

IDBG-74335 (ABCG4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017127	cholesterol transporter activity
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006200	ATP catabolic process
GO:0033344	cholesterol efflux
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR013525 ABC-2 type transporter
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00005
PF01061

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9H172