InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TP53

Summary

InnateDB Protein

IDBP-810010.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TP53

Protein Name

tumor protein p53

Synonyms

BCC7; LFS1; P53; TRP53;

Species

Homo sapiens

Ensembl Protein

ENSP00000482222

InnateDB Gene

IDBG-26364 (TP53)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1328 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.

Experimentally validated
Total	1328 [view]
Protein-Protein	1244 [view]
Protein-DNA	66 [view]
Protein-RNA	0
DNA-DNA	18 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	85 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006355

regulation of transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR002117 p53 tumour suppressor family
IPR008967 p53-like transcription factor, DNA-binding
IPR011615 p53, DNA-binding domain

PFAM

PF00870

PRINTS

PR00386

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB118156 AC007421 AC087388 DQ486039 EF178467 EF178468 EF178469 EF178470 EF445551 EF445552 EF445553 EF445554 EF445555 EF445556 EF445557 EF445558 EF445559 EF445560 EF445561 EF445562 EF445563 EF445564 EF445565 EF445566 EF445567 EF445568 EF445569 EF445570 EF445571 EF445572 EF445573 EF445574 EF445575 EF445576 EF445577 EF445578 EF445579 EF445580 EF445581 EF445582 EF445583 EF445584 EF445585 EF445586 EF445587 EF445588 EF445589 EF445590 EF445591 EF445592 EF445593 EF445594 EF445595 EF445596 EF445597 EF445599 EF445600 EF445601 EF445602 EF445603 EF445604 EF445605 EF445606 EF445607 EF445608 EF445609 EF445610 EF445611 EF445612 EF445613 EF445614 EF445615 EF445616 EF445617 EF445618 EF445619 EF445620 EF445621 EF445622 EF445623 EF445624 EF445625 EF445626 EF680844 EU523098 EU856041 JF923570 JF923571 JF923572 JQ751320 JQ751321 JQ751322 JQ751323 JQ751324 JQ751325 JQ751326 JQ751327 JQ751328 JQ751329 JQ751330 JQ751331 JQ751332 JQ751333 JQ751334 JQ751335 JQ751336 JQ751337 JQ751338 JQ751339 JQ751340 JQ751341 JQ751342 JQ751343 JQ751344 JQ751345 JQ751346 JQ751347 JQ751348 JQ751349 JQ751350 JQ751351 JQ751352 JQ751353 JQ751354 JQ751355 JQ751356 JQ751357 JQ751358 JQ751359 JQ751360 JQ751361 JQ751362 JQ751363 JQ751364 JQ751365 JQ751366 JQ751367 JQ751368 JQ751369 JQ751370 JQ751371 JQ751372 JQ751373 JQ751374 JQ751375 JQ751376 JQ751378 JQ751379 JQ751380 JQ751381 JQ751382 JQ751383 JQ751384 JQ751385 JQ751386 JQ751387 JQ751388 JQ751389 JQ751390 JQ751391 JQ751392 JQ751393 JQ751394 JQ751395 JQ751396 JQ751397 JQ751398 JQ751399 JQ751400 JQ751401 JQ751402 JQ751404 JQ751405 JQ751406 JQ751407 JQ751408 JQ751409 JQ751410 JQ751411 JQ751412 JQ751413 JQ751414 JQ751415 JQ751416 JQ751417 JQ751418 JQ751419 JQ751420 JQ751421 JQ751422 JQ751423 JQ751424 JQ751425 JQ751426 JQ751427 JQ751428 JQ751429 JQ751430 JQ751431 JQ751432 JQ751433 JQ751434 JQ751435 JQ751436 JQ751437 JQ751438 JQ751439 JQ751440 JQ751441 JQ751442 JQ751443 JQ751444 JQ751445 JQ751446 JQ751447 JQ751448 JQ751449 JQ751450 JQ751451 JQ751452 JQ751453 JQ751454 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KC820730 KC820732 KC820733 KC820734 KC820735 KC820736 KC820737 KC820740 KC820741 KC820742 KC820743 KC820744 KC820745 KC820747 KC820748 KC820749 KC820751 KC820753 KC820754 KC820755 KC820757 KC820758 KC820760 KC820761 KC820763 KC820764 KC820765 KC820766 KC820767 KC820768 KC820769 KC820770 KC820771 KC820772 KC820773 KC820774 KC820775 KC820776 KC820777 KC820778 KC820779 KC820780 KC820781 KC820782 KC820783 KC820784 KC820786

GenPept

ABF51618 ABM69023 ABM69024 ABM69025 ABM69026 ABO28385 ABO28386 ABO28387 ABO28388 ABO28389 ABO28390 ABO28391 ABO28392 ABO28393 ABO28394 ABO28395 ABO28396 ABO28397 ABO28398 ABO28399 ABO28400 ABO28401 ABO28402 ABO28403 ABO28404 ABO28405 ABO28406 ABO28407 ABO28408 ABO28409 ABO28410 ABO28412 ABO28413 ABO28414 ABO28415 ABO28416 ABO28417 ABO28418 ABO28419 ABO28420 ABO28421 ABO28422 ABO28423 ABO28424 ABO28425 ABO28426 ABO28427 ABO28428 ABO28429 ABO28430 ABO28431 ABO28432 ABO28433 ABO28434 ABO28435 ABO28436 ABO28437 ABO28438 ABO28439 ABO30992 ABO30993 ABO30994 ABO30995 ABO30996 ABO30997 ABO30998 ABO30999 ABO31000 ABO31001 ABO31002 ABO31003 ABO31004 ABO31005 ABO31006 ABO31007 ABO31008 ABO31009 ABO31010 ABO31011 ABO31012 ABV21351 ACA63978 ACF95000 AEQ16483 AEQ16484 AEQ16485 AGA62529 AGA62530 AGA62531 AGA62532 AGA62533 AGA62534 AGA62535 AGA62536 AGA62537 AGA62538 AGA62539 AGA62540 AGA62541 AGA62542 AGA62543 AGA62544 AGA62545 AGA62546 AGA62547 AGA62548 AGA62549 AGA62550 AGA62551 AGA62552 AGA62553 AGA62554 AGA62555 AGA62556 AGA62557 AGA62558 AGA62559 AGA62560 AGA62561 AGA62562 AGA62563 AGA62564 AGA62565 AGA62566 AGA62567 AGA62568 AGA62569 AGA62570 AGA62571 AGA62572 AGA62573 AGA62574 AGA62575 AGA62576 AGA62577 AGA62578 AGA62579 AGA62580 AGA62581 AGA62582 AGA62583 AGA62584 AGA62585 AGA62587 AGA62588 AGA62589 AGA62590 AGA62591 AGA62592 AGA62593 AGA62594 AGA62595 AGA62596 AGA62597 AGA62598 AGA62599 AGA62600 AGA62601 AGA62602 AGA62603 AGA62604 AGA62605 AGA62606 AGA62607 AGA62608 AGA62609 AGA62610 AGA62611 AGA62613 AGA62614 AGA62615 AGA62616 AGA62617 AGA62618 AGA62619 AGA62620 AGA62621 AGA62622 AGA62623 AGA62624 AGA62625 AGA62626 AGA62627 AGA62628 AGA62629 AGA62630 AGA62631 AGA62632 AGA62633 AGA62634 AGA62635 AGA62636 AGA62637 AGA62638 AGA62639 AGA62640 AGA62641 AGA62642 AGA62643 AGA62644 AGA62645 AGA62646 AGA62647 AGA62648 AGA62649 AGA62650 AGA62651 AGA62652 AGA62653 AGA62654 AGA62655 AGA62656 AGA62657 AGA62658 AGA62659 AGA62660 AGA62661 AGA62662 AGA62663 AGA62664 AGA62665 AGA62666 AGA62667 AGA62668 AGA62669 AGA62670 AGA62671 AGA62672 AGA62673 AGA62674 AGA62675 AGA62676 AGA62677 AGA62678 AGA62679 AGA62680 AGA62681 AGA62682 AGA62683 AGA62684 AGA62685 AGA62686 AGA62687 AGA62688 AGA62689 AGA62690 AGA62691 AGA62692 AGA62693 AGA62694 AGA62695 AGA62696 AGA62697 AGA62699 AGA62700 AGA62701 AGA62702 AGA62704 AGA62705 AGA62708 AGA62709 AGA62710 AGA62711 AGA62714 AGA62715 AGA62716 AGA62718 AGA62719 AGA62721 AGA62723 AGA62724 AGA62725 AGA62726 AGA62727 AGA62730 AGA62731 AGA62733 AGA62734 AGA62735 AGA62736 AGA62737 AGA62740 AGA62741 AGA62742 AGA62743 AGA62744 AGA62745 AGA62746 AGA62747 AGA62748 AGA62752 AGA62755 AGA62756 AGA62757 AGA62759 AGA62760 AGA62761 AGA62762 AGA62763 AGA62764 AGA62765 AGA62766 AGA62767 AGA62768 AGA62769 AGA62770 AGA62771 AGA62772 AGA62773 AGA62774 AGA62775 AGA62776 AGA62777 AGA62778 AGA62779 AGA62780 AGA62781 AGA62782 AGA62783 AGA62784 AGA62785 AGA62786 AGA62787 AGA62788 AGA62789 AGA62790 AGA62791 AGA62792 AGA62793 AGA62794 AGA62795 AGA62796 AGA62797 AGA62798 AGA62799 AGA62800 AGA62801 AGA62802 AGA62803 AGA62804 AGA62805 AGA62806 AGA62807 AGA62808 AGA62809 AGA62810 AGA62811 AGA62812 AGA62813 AGA62814 AGA62815 AGA62816 AGA62817 AGA62818 AGA62819 AGA62820 AGA62821 AGA62822 AGA62823 AGA62824 AGA62825 AGA62826 AGA62827 AGA62828 AGA62829 AGA62830 AGA62831 AGA62833 AGA62834 AGA62835 AGA62836 AGA62837 AGA62838 AGA62839 AGA62840 AGA62841 AGA62842 AGA62843 AGA62844 AGA62845 AGA62846 AGA62847 AGA62848 AGA62849 AGA62850 AGA62851 AGA62852 AGA62853 AGA62854 AGA62855 AGA62857 AGA62858 AGA62859 AGA62861 AGA62862 AGA62863 AGA62864 AGA62865 AGA62866 AGA62867 AGA62868 AGA62869 AGA62870 AGA62871 AGA62872 AGA62873 AGA62874 AGA62875 AGA62876 AGA62877 AGA62878 AGA62879 AGA62880 AGA62881 AGA62882 AGA62883 AGA62884 AGA62885 AGA62886 AGA62887 AGA62888 AGA62889 AGA62890 AGA62891 AGA62892 AGA62893 AGA62894 AGA62895 AGA62896 AGA62897 AGA62898 AGA62899 AGA62900 AGA62901 AGA62902 AGA62903 AGA62904 AGA62905 AGA62906 AGA62907 AGA62908 AGA62909 AGA62910 AGA62911 AGA62912 AGA62913 AGA62914 AGA62915 AGA62916 AGA62917 AGA62918 AGA62919 AGA62920 AGA62921 AGA62922 AGA62923 AGA62924 AGA62925 AGA62926 AGA62927 AGA62928 AGA62929 AGA62930 AGA62931 AGA62932 AGA62933 AGA62934 AGA62935 AGA62936 AGA62937 AGA62938 AGA62939 AGA62940 AGA62941 AGA62942 AGA62943 AGA62944 AGA62945 AGA62946 AGA62947 AGA62948 AGA62949 AGA62950 AGA62951 AGA62952 AGA62953 AGA62954 AGA62955 AGA62956 AGA62957 AGA62958 AGA62959 AGA62960 AGA62961 AGA62962 AGA62963 AGA62964 AGA62965 AGA62966 AGA62967 AGA62968 AGA62969 AGA62970 AGA62971 AGA62972 AGA62973 AGA62974 AGA62975 AGA62976 AGA62977 AGA62978 AGA62979 AGA62980 AGA62981 AGA62982 AGA62983 AGA62984 AGA62985 AGA62986 AGA62987 AGA62988 AGA62989 AGA62990 AGA62991 AGA62992 AGA62993 AGA62994 AGA62995 AGA62996 AGA62997 AGA62998 AGA62999 AGA63000 AGA63001 AGA63002 AGA63003 AGA63004 AGA63005 AGA63006 AGA63007 AGA63008 AGA63009 AGA63011 AGA63012 AGA63014 AGA63016 AGA63019 AGA63020 AGA63021 AGA63022 AGA63024 AGA63025 AGA63026 AGA63028 AGA63030 AGA63031 AGA63032 AGA63033 AGA63034 AGA63035 AGA63037 AGA63039 AGA63040 AGA63041 AGA63042 AGA63045 AGA63046 AGA63047 AGA63048 AGA63049 AGA63050 AGA63051 AGA63053 AGA63054 AGA63055 AGA63056 AGA63057 AGA63058 AGA63059 AGA63060 AGA63061 AGA63062 AGA63063 AGA63064 AGA63065 AGA63066 AGA63067 AGA63068 AGA63069 AGA63070 AGA63071 AGA63072 AGA63073 AGA63074 AGA63075 AGA63076 AGA63077 AGA63078 AGA63079 AGA63080 AGA63081 AGA63082 AGA63083 AGA63084 AGA63085 AGA63086 AGA63087 AGA63088 AGA63089 AGA63090 AGA63091 AGA63092 AGA63093 AGA63094 AGA63095 AGA63096 AGA63097 AGA63098 AGA63099 AGA63100 AGA63101 AGA63102 AGA63103 AGA63104 AGA63105 AGA63106 AGA63107 AGA63108 AGA63109 AGA63110 AGA63111 AGA63112 AGA63113 AGA63114 AGA63115 AGA63116 AGA63117 AGA63118 AGA63119 AGA63120 AGA63121 AGA63122 AGA63123 AGA63124 AGA63125 AGA63126 AGA63127 AGA63128 AGR27806 AGR27809 AGR27810 AGR27811 AGR27812 AGR27813 AGR27814 AGR27815 AGR27816 AGR27817 AGR27818 AGR27820 AGR27821 AGR27822 AGR27823 AGR27825 AGR27827 AGR27828 AGR27829 AGR27830 AGR27831 AGR27832 AGR27835 AGR27836 AGR27837 AGR27838 AGR27839 AGR27840 AGR27842 AGR27843 AGR27844 AGR27846 AGR27848 AGR27849 AGR27850 AGR27852 AGR27853 AGR27855 AGR27856 AGR27858 AGR27859 AGR27860 AGR27861 AGR27862 AGR27863 AGR27864 AGR27865 AGR27866 AGR27867 AGR27868 AGR27869 AGR27870 AGR27871 AGR27872 AGR27873 AGR27874 AGR27875 AGR27876 AGR27877 AGR27878 AGR27879 AGR27881 BAD11806

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca