Version 5.4
Homo sapiens Protein: MDM4
Summary
InnateDB Protein IDBP-810332.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MDM4
Protein Name MDM4, p53 regulator
Synonyms HDMX; MDMX; MRP1;
Species Homo sapiens
Ensembl Protein ENSP00000478080
InnateDB Gene IDBG-106054 (MDM4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 80 [view]
Protein-Protein 79 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0071157 negative regulation of cell cycle arrest
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR001876 Zinc finger, RanBP2-type
IPR003121 SWIB/MDM2 domain
IPR016495 p53 negative regulator Mdm2/Mdm4
PFAM PF13639
PF14634
PF00641
PF02201
PRINTS
PIRSF PIRSF006748
SMART SM00184
SM00547
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4194
UniGene
RefSeq NP_001265448
HUGO HGNC:6974
OMIM 602704
CCDS CCDS73008
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca