Homo sapiens Protein: TBC1D8B
Summary
InnateDB Protein IDBP-81244.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D8B
Protein Name TBC1 domain family, member 8B (with GRAM domain)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000310675
InnateDB Gene IDBG-81238 (TBC1D8B)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s).
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR004182 GRAM domain
PFAM PF00566
PF02893
PRINTS
PIRSF
SMART SM00164
SM00568
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0IIM8
PhosphoSite PhosphoSite-Q0IIM8
TrEMBL D6RC82
UniProt Splice Variant
Entrez Gene 54885
UniGene Hs.600760
RefSeq NP_942582
HUGO HGNC:24715
OMIM
CCDS CCDS14523
HPRD 06529
IMGT
EMBL AB449890 AB449891 AK000305 AK123957 AL391315 AL591849 BC122564
GenPept AAI22565 BAA91071 BAC85735 BAH16633 BAH16634 CAI39548 CAI40161