Homo sapiens Protein: MSH2
Summary
InnateDB Protein IDBP-812481.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSH2
Protein Name mutS homolog 2
Synonyms COCA1; FCC1; HNPCC; HNPCC1; LCFS2;
Species Homo sapiens
Ensembl Protein ENSP00000481416
InnateDB Gene IDBG-50900 (MSH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 130 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 132 [view]
Protein-Protein 132 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
Biological Process
GO:0006298 mismatch repair
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000432 DNA mismatch repair protein MutS, C-terminal
IPR007695 DNA mismatch repair protein MutS-like, N-terminal
IPR007696 DNA mismatch repair protein MutS, core
IPR007860 DNA mismatch repair protein MutS, connector domain
IPR007861 DNA mismatch repair protein MutS, clamp
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00488
PF01624
PF05192
PF05188
PF05190
PRINTS
PIRSF
SMART SM00534
SM00533
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL V9H0D5
UniProt Splice Variant
Entrez Gene 4436
UniGene
RefSeq
HUGO HGNC:7325
OMIM 609309
CCDS
HPRD
IMGT
EMBL AC079775 AC138655 L47574 L47577 L47580
GenPept AAB59566 AAB59569 AAB59572 AAY15096